Volume 17, Issue 4 (April 2019 2019)                   IJRM 2019, 17(4): 287-292 | Back to browse issues page


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Dadfar F, Bamdad K. The effect of Saliva officinalis extract on the menopausal symptoms in postmenopausal women: An RCT. IJRM 2019; 17 (4) :287-292
URL: http://ijrm.ir/article-1-1497-en.html
1- Department of Biology, Payame Noor University, Tehran, Iran.
Abstract:   (3013 Views)
Background: The menopausal symptoms are the most common problems in postmenopausal women. Due to the side effects of hormone replacement therapy, the use of medicinal herbs has increased for the treatment of menopausal symptoms.
Objective: The aim of this study was to evaluate the effect of Saliva officinalis on the decreasing of the severity of the menopausal symptoms in postmenopausal women.
Materials and Methods: The study was performed on 30 postmenopausal women aged 46–58 yr referred to the healthcare center of Darab who experienced various degrees of postmenopausal symptoms. The severity of menopausal symptoms is recorded by a Menopause Rating Scale. Participants received a 100 mg capsule of sage extract daily for 4 wk. The severity of postmenopausal symptoms was compared before and after four weeks of the consumption of sage extract.
Results: The results showed the severity of hot flashes, night sweats, panic, fatigue, and concentration had significant differences before and after the consumption of sage extract.
Conclusion: It was concluded that Saliva officinalis were effective to change the severity of some of the menopausal symptoms in postmenopausal women.
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Type of Study: Original Article |

References
1. [1] Speroff L, Fritz MA. Clinical Gynecologic Endocrinology and Infertility. 7 ℎ Ed. Lippincott Williams & Wilkins, country;2005.
2. [2] Politi MC, Schleinitz MD, Col NF. Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis. J Gen Intern Med 2008; 23: 1507-1513.
3. [3] Abernethy K. The Menopause and HRT. 1 Ed. London, Philadelphia: Bailliere Tindall; 1997.
4. [4] Bommer S, Klein P, Suter A. First time proof of sage's tolerability and efficacy in menopausal women with hot flushes. Adv Ther 2011; 28: 490-500.
5. [5] Shayan A, Forouhari S, Ahmadinia H. The Effect of Body Mass Index on Sexual Function. Res J Pharm, Biol Chem Sci 2015; 6: 815-820.
6. [6] Berek JS. Novak's Gynaecology. 16th ed. Philadelphia: Lippincott Williams & Wilkins; 2012.
7. [7] North American Menopause Society. The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women: 2007 position statement of the north American menopause society. Menopause 2007; 14: 355-369.
8. [8] LaCroix AZ, Chlebowski RT, Manson JE, Aragaki AK, Johnson KC, Martin L, et al. Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy a randomized controlled trial. JAMA 2011; 305: 1305-1314.
9. [9] Pachman DR, Jones JM, Loprinzi CL. Management of menopause-associated vasomotor symptoms: Current treatment options, challenges and future directions. Int J Women's Health 2010; 2: 123-127.
10. [10] Hickey M, Elliott J, Davison SL. Hormone replacement therapy. BMJ 2012: 344: e763. [11] Borrelli F, Ernst E. Alternative and complementary therapies for the menopause. Maturitas 2010; 66: 333-343.
11. [12] Gollschewski S, Kitto S, Anderson D, Lyons-Wall P. Women's perceptions and beliefs about the use of complementary and alternative medicines during menopause. Complement Ther Med 2008; 16: 163-168.
12. [13] Ciotta L, Stracquadanio M, Pagano I, Andò A, Valenti O, Roccasalva L. Clinical effects of treatment with phytoestrogens in postmenopausal women. Minerva Ginecol 2012; 64: 15-22.
13. [14] Ernst E. ESCOP Monographs: The Scientific Foundation for Herbal Medicinal Products. European Scientific Cooperative on Phytotherapy. Focus Altern Complement Ther 2010; 15: 71-72.
14. [15] Prodan M, Tabra V. Research concering the increase of herb of culinary Sage through certain cultivation technologyies in the conditions of the didactic station in Temisoarna in 2007. Agri Sci 2010; 42: 115-118.
15. [16] kalvandi R, Alimohammadi Sh, Pashmakin Z, Rajabi M. Ehe effective of medicinal plants of Melissa officinalis and Saliva officinalis on primary dysmenorrhea. Avicenna J Clin Med 2014; 21: 105-111.
16. [17] Baghdari N, Akbari A, Ayati S, Emami A, Esmaeili H. Effect of powder of flaxseed on hot flashes in women at the climactrics. Iran J Obstet Gyneocol Infertil 2011; 14: 37-47.
17. [18] Nahidi F, Zare E, Mojab F, Alavi Majd H. The effect of Licorice root extract on hot flashes in menopause. Pajoohandeh J 2011; 16: 11-17.
18. [19] Enjezab B, Faraj-Khoda T, Khoshbin A, Mozaffari-khosravi H. Effect of Glycine max on hot flashes in postmenopausal women. J Shahid Sadoughi Univ Med Sci 2009; 17: 242-
19. [20] Akbar A, Tariq M, Nisa M. Pharmacological studies on Salvia haematodes Wall. Acta Tropl 1985; 42: 371-379.
20. [21] Karami M, Shamirani MA, Alemy SH, Gohari AR, Ehsani vostacolaee S. Comparison antinociceptive activity of the aqueous methanolic extracts of Salvia Hypoleuca and Phytolacca Americana in mice. Eur Rev Med Pharmacol Sci 2013; 17: 2755-2759.
21. [22] Sadeghi AH, Bakhshi M, Behboodi MZ, Goodarzi S,Haghani H. [Effect of sage extract on hot flashes in postmenopausal women.] Complement Med facul Nurs Midwifery 2013; 4: 324-335. (in Persian)
22. [23] De Leo V, Lanzetta D, Cazzavacca R, Morgante G. Treatment of neurovegetative menopausal symptoms with a phytotherapeutic agent. Minerva Ginecol 1998; 50: 207-
23. [24] Bommer S, Klein P, Suter A. First time proof of sage's tolerability and efficacy in menopausal women with hot flushes. Adv Ther 2011; 28: 490-500.
24. [25] Adaay MH, Al-Dujaily SS, Khazzal FK. Effect of aqueous extract of Medicago sativa and Salvia officinalis mixture on hormonal, ovarian and uterine parameters in mature female mice. J Mater Environ Sci 2013; 4: 424-433.
25. [26] Gallagher J. Salvia officinalis for menopausal hot flushes: a pilot study. Focus on Alternative and Complementary Therapies 2002; 7: 92-93.
26. [27] Vandecasteele K, Ost P, Oosterlinck W, Fonteyne V, Neve WD, Meerleer GD. Evaluation of the efficacy and safety of Salvia officinalis in controlling hot flashes in prostate cancer patients treated with androgen deprivation. Phytother Res 2012; 26: 208-213.
27. [28] Kiani rad S, Forouhari S, Samsami Dehghani A, Vafaei H, Sayadi M, Asadi M. The effect of salvia officinalis tablet on hot flashes, night sweating, and estradiol hormone in postmenopausal women. Int J Med Res Health Sci 2016; 5: 257-263.

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